Identification of the sequence encoding N-acetylneuraminate-9-phosphate phosphatase

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Identification of the sequence encoding N-acetylneuraminate-9-phosphate phosphatase.

The synthesis of N-acetylneuraminate (Neu5Ac), the main form of sialic acid, proceeds in vertebrates through the condensation of N-acetylmannosamine 6-phosphate and phosphoenolpyruvate to Neu5Ac-9-phosphate, followed by the dephosphorylation of the latter by a specific phosphatase. The sequence encoding Neu5Ac-9-phosphate phosphatase (Neu5Ac-9-Pase; E.C. 3.1.3.29) has not been determined until ...

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ژورنال

عنوان ژورنال: Glycobiology

سال: 2005

ISSN: 1460-2423,0959-6658

DOI: 10.1093/glycob/cwj050